🧠 What Experts Say About Managing MCAS & Histamine Intolerance
Managing Mast Cell Activation Syndrome (MCAS) and Histamine Intolerance requires a nuanced, science-backed approach. We’ve drawn from the insights of leading functional medicine practitioners, immunologists, and nutrition experts to bring you the most practical and up-to-date guidance.
🗣️ Expert Insights Include:
Dr. Lawrence Afrin, one of the foremost researchers on MCAS, emphasizes the importance of individualized care. He notes that symptoms can be vastly different from person to person, making personalized protocols essential for effective management.
“MCAS can affect virtually every organ system. The key to management is identifying and minimizing each individual’s unique triggers.”
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Dr. Tina Peers, a UK-based expert in histamine intolerance, highlights the role of nutrition and enzyme support in reducing symptoms.
“For many people, a low-histamine diet combined with DAO supplementation can dramatically improve quality of life.”
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Dr. Becky Campbell, author of The 4-Phase Histamine Reset Plan, focuses on root causes and recommends targeting gut health, inflammation, and stress as key steps.
“Histamine intolerance is often a sign of deeper imbalances—healing the gut and calming the nervous system are vital for long-term relief.”
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Dr. Theoharides, a mast cell researcher, recommends natural compounds like luteolin and quercetin as non-pharmaceutical options to help stabilize mast cells and reduce inflammatory responses.
“Bioflavonoids like luteolin can calm hyperactive mast cells without the side effects of many drugs.”
✅ Common Expert-Backed Strategies:
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Low-Histamine Diet (eliminate fermented, aged, and processed foods)
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DAO Enzyme Supplementation before meals
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Mast Cell Stabilizers like quercetin, luteolin, and vitamin C
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Nervous System Support through meditation, vagal nerve stimulation, or adaptogens
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Gut Repair Protocols including glutamine, probiotics, and anti-inflammatory herbs
⚠️ Our Reminder:
Every body is different. These expert suggestions are starting points—not prescriptions. Always work with a knowledgeable healthcare provider to build your own tailored plan.